Closely attached to the body surface (chest area, upper arm, wrist, ear), pulse beat, heart rate, blood oxygen, body fluid, body fat, muscle functions, or brain activity become measurable. These medical standard values and combinations thereof are of importance to physicians. Measurements support conclusions on the patient’s well-being, psyche, possible diseases, drug effectiveness, or the success of medical treatment. With increasing age or changes in life situations, medical parameters can change without being recognized by the patient and until physical complaints and symptoms have occurred. Monitoring Body and Vital Functions of Seniors A non-invasive biosensing technology platform for continuous measurement of vital functions is Bioelectrical Impedance Spectroscopy (BIS). Based on a capacitive detection method, variations in the permittivity and conductivity of cell membranes within the patient’s body become measurable. Benefits from this technology can be the monitoring and prevention of dehydration. Other medical standard values can be body-fluid content, fat content, cell mass, total body water, extracellular water, intracellular water, fat mass, or lean body mass. In addition, researchers recognize the potential of Near-Infrared Spectroscopy (NIRS) as a non-invasive detection method for continuous self-monitoring of body and vital functions. Based on an optical detection method, the transmittance and absorbance rate of light in the near-infrared region of the electromagnetic spectrum (wavelengths in the 780nm to 2,500nm range) characterize molecular absorption and reflection patterns. Benefits are monitoring of brain functions, blood circulation, blood oxygen saturation, or cardiac output levels. The near future will hold many more biosensing methods also more combined complementary detection methods in diagnostic devices. New sensors and better diagnostic detection methods will provide better insights into the characteristics of analytes and optimize the sensitivity, accuracy, and reliability of these detection methods, and to the benefit of senior health.